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    Wednesday, June 23, 2004

    Superboy: There's a fascinating article in this week's New England Journal of Medicine about a super strong toddler who has a genetic defect in a muscle-controlling gene called myostatin. When the gene is inhibited, or not expressed, the muscles develop disproportionately large. Interestingly, the same mutation slows the development of fat cells. Go figure.

    There's a picture of the little boy's muscular legs on the main page of the New England Journal. An accompanying perspective article notes that cattle producers have long been aware of this gene. The Belgian Blue breed in particular is known for it. Baby Belgian Blues are so big that their mother's risk death delivering them, and are often delivered by C-section. Poor things.

    But I digress. The article is interesting for what it says about the role of genetics in our body morphology. The little boy is unusually strong for a toddler. His mother was a professional athlete, and her family has many members who are unusually strong. Some of us really can work a lot less and have less fat than others. Genetics and basic metabolism do matter.

    (One odd thing, the genogram the article provides leaves out the child's father completely. It looks as if he sprang de novo from his mother. Is he a clone? Or is there just no way to represent two ships that passed in the night so lightly that one knows absolutely nothing about the other?)


     

    posted by Sydney on 6/23/2004 11:34:00 PM 0 comments

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